# Make a payment to the MHRA Source: https://www.keypedia.com/records/uk_mhra_guidance/uk-mhra/9c12064b-e775-4b61-8ddd-ead7a46e4d55 Type: Detailed Guide Published: December 18, 2014 Updated: September 2, 2025 > The UK Medicines and Healthcare products Regulatory Agency (MHRA) provides instructions for settling invoices related to its regulatory services. This guidance applies to all companies interacting with the agency, excluding those specifically utilizing the Device Online Registration System. Governed by the Fees Regulations, the agency requires immediate payment upon the receipt of an invoice. Failure to comply with these payment terms can lead to significant consequences, including the accrual of penalty fees, the suspension of existing licenses or authorizations, and legal proceedings for debt recovery. Payments must be made via the secure GOV.UK online portal using credit or debit cards or through electronic bank transfers; the MHRA no longer accepts cheques or postal documentation. Required actions for applicants include quoting specific invoice and customer numbers on all transactions and ensuring that internal Purchase Orders are submitted before invoicing to avoid delays. The guidance emphasizes that internal administrative processes cannot justify withholding payment. Specific contact channels are provided for various departments, including Clinical Trials and Inspections, to address disputes or account queries. To ensure compliance, businesses must send electronic remittance advice to the designated MHRA email address once transfers are completed. --- ## Content Who can use this service This service can be used for all payments to MHRA with the exception of Device Registration and Certificates of Free Sale fees that must be paid directly through the Device Online Registration System (DORS), using Worldpay or BACS/CHAPS. For further information on Device Registration fees see Register medical devices to place on the market . For further information on Certificates of Free Sale see Certificates of Free Sale for exporting medical devices . Payments Once your application has been validated you will receive an invoice to allow you to make payment for the outstanding amount. All invoices must be settled upon receipt of invoice. Penalty fees may be incurred for non-payment. Details of the penalties are set out in the Fees Regulations . Non-payment may also result in suspension of any licence or authorisation, followed by legal proceedings for any unpaid amounts, as a debt due to the Crown. Please ensure you quote relevant invoice and customer number when making payment. How to pay online using credit or debit card Access secure online payments service - GOV.UK Pay . You can pay online for a range of our services 24 hours a day, 7 days a week using your credit or debit card. We accept debit cards (DC) - Maestro; Delta; Visa Electron and credit cards (CC) – Mastercard, Visa and American Express. Please ensure you quote the relevant invoice number when making a payment. See the terms and conditions for making a payment by credit and debit card . Bank transfer You can make a bank transfer to remit payment of invoices. Please ensure that the relevant invoice number is quoted when making payment so that the funds can be correctly allocated. Account details: account name: MHRA account number: 10004386 sort code: 60-70-80 swift code: NWBKGB2L IBAN: GB68NWBK60708010004386 National Westminster Bank RBS, London Corporate Service Centre, 2nd Floor 280 Bishopsgate London EC2M 4RB Please send your remittance advice notices to remittances@mhra.gov.uk and ensure the relevant invoice number is quoted on the remittance advice. We are unable to accept any documentation sent to us by post. Cheques are no longer accepted We no longer accept cheques; please pay by credit or debit card or pay electronically by Bank transfer . Purchase Orders (POs) and non-payments It is the responsibility of the applicant to ensure timely payment of invoices for their submissions. If your organisation operates a PO system, please ensure the relevant PO is provided to MHRA before the invoice is issued. Refusal to pay outstanding fees on the grounds that a PO is not provided on invoice will not be accepted; the use of POs is an internal control process and cannot be used as a reason to withhold payment of legitimate invoices.b Invoice disputes/queries For invoice disputes/queries, please contact relevant MHRA departments. Clinical Investigations CI-applications@mhra.gov.uk and Ci-amendments@mhra.gov.uk . British Pharmacopeia (BP) BPCRS@mhra.gov.uk Clinical Practice Research Datalink (CPRD) cprdenquiries@mhra.gov.uk Clinical Trial Applications (CTA invoices) ctdhelpline@mhra.gov.uk Export certificate exports@mhra.gov.uk Inspections inspectionplanning@mhra.gov.uk National Institute for Biological Standards and Controls (NIBSC) standard@nibsc.org Process Licence (PCL) PCL@mhra.gov.uk Product Licence submissions RIS.NA@mhra.gov.uk Product License (Parallel Import) PLPI_submissions@mhra.gov.uk Product Licence Variation applications variationqueries@mhra.gov.uk RamaXL portal.manager@mhra.gov.uk Serious Adverse Blood Reactions & Events (Sabre) Sabre@mhra.gov.uk Scientific Advice Meetings (SAM) scientific_advice@mhra.gov.uk Tobacco Products Directive, E-cigarette unit (TPD) TPDnotifications@mhra.gov.uk For any queries relating to the customer account status or payment/s update please contact MHRA Accounts Receivable department: Ledger Split Extension Number Customers A-C 0203 080 6087 Customers D-K 0203 080 6968 Customers L-P 0203 080 6167 Customers Q-T 0203 080 6075 Customers V-Z 0203 080 6530 ## Attachments - [iRIS user guide](https://assets.publishing.service.gov.uk/media/5a758c4440f0b6360e474f41/iRIS_user_guide.pdf) - [terms and conditions for making a payment by credit and debit card](https://assets.publishing.service.gov.uk/media/60c72546d3bf7f4bd9814e93/Terms_and_conditions_for_credit_or_debit_card_payments.pdf)