JO Cosmetics Co., Ltd. – FDA 483, May 22, 2025

JO Cosmetics Co., Ltd. in Hanyu, Japan, was cited for significant deficiencies in its quality control and data integrity systems during an FDA inspection. Observations included a failure to investigate manufacturing discrepancies, inadequate controls for microbial contamination, poor computer system security, and a lack of annual visual examination of reserve samples. These issues indicate a general lack of adherence to good manufacturing practices.