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Detailed GuideMHRA

Clinical trials for medicines: non-investigational medicinal products

Guidance on using non-investigational medicinal products in a clinical trial.

First published: Jun 24, 2025Last updated: Apr 27, 2026Changes: 5

Latest change: The amended Clinical Trials Regulations took full effect on 28 April 2026. As such, this guidance should now be considered effective and is no longer in draft.

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