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GuidanceMHRA

Get more help to apply for medicines Integrated Scientific Advice (ISA)

Extra information for the Medicines and Healthcare products Regulatory Agency (MHRA) and National Institute for Health and Care Excellence (NICE) Integrated Scientific Advice (ISA) service.

First published: Feb 20, 2026Last updated: Mar 16, 2026Changes: 2

Latest change: Changes made to update the document Scientific Advice (ISA) service application questions

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