GuidanceMHRA
Clinical Trials Regulations enforcement provisions
Information about Clinical Trials Regulations outlining expanded enforcement provisions, offences, and compliance requirements for sponsors and investigators.
First published: Jan 12, 2026Last updated: Apr 27, 2026Changes: 3
Latest change: The amended Clinical Trials Regulations took full effect on 28 April 2026. As such, this guidance should now be considered effective and is no longer in draft.
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