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Detailed GuideMHRA

Clinical trials for medicines: Compliance with ICH E6 good clinical practice (GCP) in the United Kingdom

Information on how ICH E6(R3) good clinical practice (GCP) principles are implemented and enforced in UK clinical trial legislation.

First published: Mar 27, 2026Last updated: Apr 27, 2026Changes: 3

Latest change: The amended Clinical Trials Regulations took full effect on 28 April 2026. As such, this guidance should now be considered effective and is no longer in draft.

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